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Daily reminder that ELF to upper microwave band radiation interacts with the voltage sensing sub-unit of voltage gated calcium channels, leading to chronically elevated intracelluar calcium, overactivity of Ca2+ regulated machinery and processes, and ultimately increased NO synthesis that cannot be properly processed through standard channels and thus in the presence of superoxide forms peroxynitrite. Ignoring the high level signalling and regulatory functions of VGCCs (such as neurotransmitter release in the CNS, as well as synapse and dendritic spine maintenance / formation), this is the low level mechanism leading to oxidative and nitrosative stress, and subsequent DNA damage and deleterious effects on other cellular structures. This entire chain of effects is completely eliminated by VGCC blockers both in cultured cell lines, and in vivo. The influx of extracellular calcium is also immediate upon exposure, <5s, further suggesting that microwaves are indeed acting on the charge groups comprising the VGCC's voltage sensor. Given their location in the plasma membrane and what we know about the physics of pulsed fields, this is the most plausible.
In summary, Wi-Fi and cellular phones are making you infertile and raising the probability of issues in your offspring, raising your risk of various cancers, giving rise to widespread psychiatric issues, and bluntly giving you brain damage outright. Rates of autism will continue to rise along with spontaneous abortion and other causes of infant mortality, and complex society will likely crumble as people succumb to early onset Alzheimer and dementia. What follows is an inability to naturally produce viable offspring. Say nothing of broader ecological collapse from the death of other organisms.
Have fun. This is the future we chose.
out of africa is bullshit prove me wrong
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malaria has been found in mosquitoes in amber up to 30 million years old. it infects primates, it infected early hominids, and it infects humans. It has had severe effects on human evolution, with multiple common traits existing purely to counter it
-glucose 6 phosphate deficiency seen in 10-15% of black males and many carriers for the trait
-sickle trait seen in up to 10% of blacks
-thalassemias are another group of diseases that exist purely because being a carrier of the trait is protective against malaria
all of these traits are so common that almost every single person in africa at this point is a carrier of at least one trait that protects against malaria. these traits are recessive traits, and confer only advantages to carriers. the sheer frequency and different number of these traits to survive malaria shows how important it has been in evolution of humans in africa.
but somehow, in just the 10,000 years since humans "left" africa, all of these recessive traits are barely even found in northern europe!! somehow, in just 10,000 years, a recessive trait that has no bad effects was selected out of the entire population to the point they are not seen in entire populations in northern europe. how can this be? assuming the frequency became low enough, sickle disease would only manifest in like 1 in 100k people there but the carrier state should still be at least like 1%. but it is not seen at all outside of some admixture from africa in spain, and this is the case in MULTIPLE traits against malaria.
so how can this be? simple. out of africa is bullshit. I am going to post the frequencies of the various traits that protect against malaria, and you can analyze for yourself and try to work the mental gymnastics to salvage the so called out of africa theory.
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>open up a book on mathematical foundations, eager to learn about how to define 'set'
>"Set is a collection of objects. We denote a set like this... relations..."
>Drop the book into a garbage bin.
The first sentence should have been the last sentence of the book I am looking for.
What's the most rigorous, unambiguous, exact explanation/book you know on the foundations on mathematics/logic? Like if alien came here and didn't understand a word you said, but had a high capacity to learn and was blind, what would be the best way to teach him math?
Critical Thinking Toolkit
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Have you ever felt that you were able to understand the world better after learning, for example, thermodynamics, even in topics totally unrelated to chemistry and physics? Have you ever noticed that the "patterns & structures of thought" seem to repeat themselves in science, philosophy, and even literature?
What about encountering books that were substantial enough to affect your life after thinking and applying its ideas? Do you consider a certain text to be "foundational" for those in pursuit of knowledge?
I'm hoping to create a list of 15-20 books, in a variety of subjects, that will increase clarity & depth of thought, leaving autodidacts with the mental faculties necessary to tackle future challenges. I would also like to have this list of books be sufficient to achieve a cursory education for people looking to improve their knowledge beyond the dregs of their high school or college education, though this isn't as important.
I need to keep the scope limited to the fundamentals. There are far more than 20 worthwhile books, and this isn't a definitive guide to "the best books ever". Some fields like "economics" may already require proficiency in basic fields like history, mathematics, and philosophy, so it would be redundant to cover include them. Only the bare necessities should be maintained for brevity.
Scientists are planning Washington March for Science
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>Scientists in the United States are mobilising to organise a March for Science. What originated online as a discussion about how to push back against the anti-science stance of Donald Trump’s administration rapidly gathered support from concerned scientists and non-scientists alike. A march on Washington similar to the Women’s March was proposed, and within 24 hours the group’s Twitter account had gained an additional 124,000 followers. Over half a million people have also joined a new Facebook page, which has become a hive of comments, suggestions and coordination. An event in the US capital is planned for March, with activities occurring in other countries.
>The leaders of March for Science stress that it is an inclusive movement – organising and participating in marches isn’t restricted to practising scientists. An online form that helps coordinate involvement has received thousands of contributions. What’s become clear is that this is an issue that both scientists and non-scientists are passionate about.